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Kawasaki disease symptoms , diagnosis and treatment

This is a discussion of  Kawasaki disease regarding its incidence , causes , diagnosis and management .
it is a Systemic disease affecting children under 5 years. It is also called mucocutaneous lymph node $.
 It predorninately occurs in Japan
. It may be associated with mycoplasma and HIV infection In some cases.

What are the symptoms and signs of  Kawasaki disease ?

Kawasaki disease

• Fever then bilateral conjunctival congestion, dryness and redness of Lips and oral cavity, redness of the palms and soles.
• Vasculitis in the coronary arteries with coronary aneurysm or myocardial infarction. Myocarditis or
pecicarditis may occur.
• Cervical lymph node enlargement.

Investigations:

• ++ TLC, ++  ESR, ++  CRP, thrombocytosis.
• Positive anti-endothelial cell antibodies ..
• Two-dimensional echo or anqioqraphv to detect coronary aneurysms.

How to treat Kawasaki disease ?

Treatment
• Intravenous gamrna globulins 400 mg/kg/d 4 consecutive days, followed after the acute phase by aspirin 200<300 d="" mg="" p="">• Steroids should be avoided because worserunq tho coronary artery dilatation.
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Tamer Mobarak

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