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Globus and Mallory Weiss syndrome definition and causes

These are two known esophageal diseases .

What is meant by esophageal globus ?

(Globus hystericus is an old name)
- It is persistent or intermittent sensation of a lump or foreign body in the throat, this sensation is present between meals.

Absence of dysphagia on swallowing.
- In the majority, it is probably a functional disease .
- It is treated by reassurance with anti-reflux therapy.

What is Mallory Weiss syndrome  ?

- It is a linear mucosal tear at the esophageo-gastric junction produced by a sudden increase in the intra-abdominal pressure.

- It usually occurs after a bout of coughing, retching or after an alcohol binge.
- It is diagnosed by endoscopy.

- The hemorrhage stops spontaneously. Rarely surgery with oversewing of the tear may be required.
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Tamer Mobarak

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