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Adolescent Health

๐Ÿ“‹ Key Information Summary

๐Ÿ“‹
  • Adolescence spans 10โ€“24 years and encompasses early (10โ€“13), middle (14โ€“17), and late (18โ€“24) stages, each with distinct physical, cognitive, and psychosocial milestones.
  • Tanner staging (Sexual Maturity Rating) is the standard clinical tool for assessing pubertal progression; familiarity with normal sequences is essential to distinguish variants from pathology.
  • Delayed puberty is defined as absence of secondary sexual characteristics by age 13 years in girls or 14 years in boys; constitutional delay of growth and puberty (CDGP) accounts for >60% of cases and is a diagnosis of exclusion.
  • Precocious puberty (secondary sexual characteristics before age 8 in girls or 9 in boys) requires urgent endocrine evaluation to distinguish central (GnRH-dependent) from peripheral causes.
  • Screen every adolescent for depression using validated tools (PHQ-A, KADS) at least annually; prevalence in Australian adolescents is approximately 12โ€“15%.
  • Suicide is the leading cause of death in Australians aged 15โ€“24 years; any disclosure of suicidal ideation requires immediate risk assessment using the Columbia Suicide Severity Rating Scale (C-SSRS) and a collaborative safety plan.
  • Fluoxetine is first-line pharmacotherapy for moderate-to-severe adolescent depression in Australia (PBS General Benefit), always combined with psychological therapy (CBT or IPT-A).
  • Under Australian law, a competent "mature minor" can consent to medical treatment without parental involvement; use the HANE framework (History, Assessment, Needs, Engagement) to guide confidential consultations.
  • HEADSS assessment (Home, Education/Employment, Activities, Drugs, Sexuality, Suicide/depression) should be used routinely to screen for risk behaviours in a structured, non-judgemental manner.
  • Aboriginal and Torres Strait Islander adolescents experience disproportionately higher rates of self-harm, substance use, STIs, and teenage pregnancy; culturally safe, trauma-informed care is essential.
  • HPV vaccination (Gardasil 9) on the National Immunisation Program at age 12โ€“13 and chlamydia screening from age 15 for sexually active adolescents are key preventive interventions.
  • Substance use screening using CRAFFT 2.1 or AUDIT-C should be integrated into routine adolescent consultations; brief intervention and motivational interviewing are effective first-line responses.
  • Refer complex presentations to Headspace (12โ€“25 years), local Child and Adolescent Mental Health Services (CAMHS), or paediatric endocrinology as appropriate.

Introduction & Australian Epidemiology

Adolescence is a critical developmental period spanning approximately 10 to 24 years of age, characterised by rapid biological, psychological, and social change. General practitioners (GPs) are often the first point of contact for adolescents and play a central role in early identification of developmental concerns, mental health conditions, and risk behaviours. In Australia, approximately 16% of the population (over 4 million people) are aged 10โ€“24 years, and this group accounts for a significant proportion of primary care consultations.

The Australian Institute of Health and Welfare (AIHW) reports that the leading causes of morbidity and mortality in Australian adolescents are mental health conditions, self-harm, unintentional injury, and substance use. Suicide remains the leading cause of death among Australians aged 15โ€“24, with rates significantly higher among males, Aboriginal and Torres Strait Islander youth, and those in rural and remote areas. Despite this burden, adolescents are frequent "no-shows" in general practice, and when they do attend, critical issues may go unaddressed if consultations are not structured to facilitate disclosure.

โš ๏ธ
Consultation tip: Always offer the adolescent time alone without a parent or carer. This single action significantly increases disclosure of sensitive issues including mental health concerns, substance use, and sexual health.

Key epidemiological data for Australian adolescents:

  • Approximately 1 in 7 (14%) Australians aged 4โ€“17 experience a mental health condition in any given year (ABS National Study of Mental Health and Wellbeing).
  • Self-harm presentations to emergency departments have increased by over 50% in the 12โ€“17 age group over the past decade (AIHW, 2023).
  • Chlamydia is the most commonly notified STI in Australia, with the highest notification rates in the 15โ€“24 age group.
  • Approximately 20% of Year 10 students report having consumed alcohol in the past week (ASSAD survey data).
  • Obesity prevalence in adolescents aged 12โ€“17 is approximately 8%, with a further 20% classified as overweight (ABS National Health Survey).

Adolescent Development Stages & Sexual Development

Understanding normal adolescent development is the foundation of effective clinical care. Development progresses through three broad stages, each with characteristic physical, cognitive, and psychosocial features. Clinicians must recognise normal variation to avoid unnecessary investigation while remaining vigilant for pathological processes.

Developmental Stages

Stage Age Range Physical Cognitive Psychosocial
Early adolescence 10โ€“13 years Puberty onset; growth spurt; breast budding / testicular enlargement; early pubic hair Concrete operational thinking transitioning to early abstract thought; egocentrism Peer conformity; body image concerns; emerging independence from parents; mood lability
Middle adolescence 14โ€“17 years Peak height velocity; near-adult body habitus; menarche (girls) / spermarche (boys); acne Formal operational thought; idealism; capacity for abstract reasoning Identity exploration; romantic/sexual relationships; risk-taking behaviour peaks; peer group paramount
Late adolescence 18โ€“24 years Adult physique; growth plates fused; completion of sexual maturation Consolidated abstract thought; capacity for long-term planning; nuanced moral reasoning Identity consolidation; vocational focus; transition to independent health care; intimate partnerships

Tanner Staging (Sexual Maturity Rating)

Tanner staging (also known as Sexual Maturity Rating, SMR) provides a standardised method for documenting pubertal progression. It is based on the sequential development of secondary sexual characteristics and is graded from 1 (prepubertal) to 5 (adult). Self-assessment questionnaires with illustrated staging are available for use in clinical practice and are preferred by both patients and clinicians where direct examination is not clinically indicated.

Tanner Stage Females โ€” Breast Females โ€” Pubic Hair Males โ€” Genitalia Males โ€” Pubic Hair
Stage 1 (prepubertal) No breast elevation; areola follows chest wall contour No pubic hair (vellus hair only) Testes <4 mL; prepubertal penis No pubic hair (vellus hair only)
Stage 2 Breast budding; elevation of areola and papilla Sparse, lightly pigmented hair along labia Testicular enlargement โ‰ฅ4 mL; scrotal thinning Sparse, lightly pigmented hair at base of penis
Stage 3 Further breast and areola enlargement; no separation of contours Darker, coarser, curlier hair spreading over pubis Penile lengthening; further testicular growth Darker, coarser hair spreading over pubis
Stage 4 Areola and papilla form secondary mound; typically 1โ€“2 years post-menarche Adult-type hair; no medial thigh spread Penile widening and glans development; adult-sized testes Adult-type hair; no medial thigh spread
Stage 5 (adult) Adult contour; areola recessed to breast contour Adult distribution with medial thigh extension Adult genitalia Adult distribution with medial thigh extension

Key Developmental Milestones

  • Females: Thelarche (breast budding, Tanner 2) is typically the first sign of puberty, occurring at a mean age of 10.5 years (range 8โ€“13). Menarche occurs at a mean age of 12.5 years, usually at Tanner stage 3โ€“4. Peak height velocity (PHV) precedes menarche by approximately 1 year (mean 9 cm/year).
  • Males: Testicular enlargement โ‰ฅ4 mL (Tanner 2) is the first sign of puberty, occurring at a mean age of 11.5 years (range 9โ€“14). PHV occurs at Tanner stage 3โ€“4 (mean 9โ€“10 cm/year). Spermarche (first ejaculation) typically occurs around age 13.
  • Normal variants: Asynchronous development (e.g., isolated pubic hair adrenarche without thelarche, or unilateral breast budding) is common and usually benign but warrants follow-up if progression does not occur within 6โ€“12 months.
โ„น๏ธ
Clinical pearl: The timing of puberty has shifted earlier over the past several decades, particularly in girls. Population data suggest that thelarche before age 8 may affect up to 15% of girls, though most do not have pathological precocious puberty. Clinical assessment of progression rate and bone age remains essential.

Delayed & Precocious Puberty

Delayed Puberty

Delayed puberty is defined as the absence of any signs of secondary sexual development by age 13 years in girls or 14 years in boys. It affects approximately 2โ€“3% of adolescents and causes significant psychosocial distress. The most important clinical task is distinguishing constitutional delay of growth and puberty (CDGP) โ€” a benign, self-limited variant โ€” from pathological causes requiring treatment.

Most Common
Constitutional Delay of Growth and Puberty (CDGP)
Accounts for >60% of delayed puberty in both sexes. Family history of "late bloomer." Bone age delayed by โ‰ฅ2 years. Growth velocity normal for bone age. Short stature but predicted adult height within target range.
Setting: GP monitoring with reassurance; endocrine referral if diagnostic uncertainty
Secondary Hypogonadism
Hypothalamicโ€“Pituitary Causes
Kallmann syndrome (anosmia + hypogonadism), functional hypothalamic amenorrhoea (excessive exercise, low BMI, chronic illness), pituitary tumour, chronic systemic disease (coeliac, IBD, CF, renal failure).
Setting: Paediatric endocrinology assessment required
Primary Hypogonadism
Gonadal Causes
Turner syndrome (45,X โ€” short stature, streak gonads), Klinefelter syndrome (47,XXY โ€” tall stature, small firm testes), gonadal dysgenesis, chemotherapy/radiation-induced gonadal failure.
Setting: Urgent paediatric endocrine referral; karyotype indicated

Investigations for Delayed Puberty

Essential Bone age (left wrist X-ray) Determines skeletal maturity; CDGP shows bone age delayed โ‰ฅ2 years. MBS Item 57522.
Essential FSH, LH, oestradiol (girls) / testosterone (boys) Prepubertal levels suggest hypogonadism; must be interpreted with clinical context. Fasting morning sample preferred.
Essential TFTs (TSH, free T4) To exclude hypothyroidism as a reversible cause of delayed puberty.
Available IGF-1, GH provocation testing If short stature disproportionate to bone age; GH deficiency is a pathological cause.
Available Karyotype Indicated in suspected Turner or Klinefelter syndrome; consider in all girls with primary amenorrhoea and elevated FSH.
Available Pelvic ultrasound To assess uterine and ovarian morphology; helpful in differentiating CDGP from gonadal dysgenesis in girls.
Available Coeliac serology, FBC, ESR/CRP, ferritin, zinc To exclude chronic illness (coeliac disease, IBD, malnutrition, zinc deficiency) as causes of delayed puberty.

Treatment of Delayed Puberty

๐Ÿ’Š
Oestradiol (for girls with hypogonadism)
Progynovaยฎ ยท Generic ยท Oestrogen
Indication Induction of puberty in girls with primary or secondary hypogonadism
Starting dose Oestradiol 1โ€“2 ยตg/kg/day (equivalent to ethinyloestradiol 2โ€“2.5 ยตg/day) PO; or oestradiol valerate 0.5 mg PO daily
Titration Increase dose gradually over 2โ€“3 years to adult replacement (oestradiol valerate 2 mg PO daily); add cyclical progesterone after 2 years or when breakthrough bleeding occurs
Paediatric dose Commence at lowest dose and titrate according to Tanner staging and bone age
Renal adjustment None required
PBS status โœ” PBS General Benefit
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Testosterone (for boys with hypogonadism)
Primoteston Depotยฎ ยท Reandron 1000ยฎ ยท Androgen
Indication Induction of puberty in boys with primary or secondary hypogonadism
Starting dose Testosterone enanthate 50 mg IM every 4 weeks; or testosterone undecanoate 40โ€“80 mg PO daily (oral); titrate over 3โ€“4 years to adult replacement
Adult dose Testosterone undecanoate 1000 mg IM (Reandron) every 10โ€“14 weeks; or testosterone enanthate 200โ€“250 mg IM every 2โ€“3 weeks
Monitoring Testosterone level, LFTs, FBC (polycythaemia risk), lipids, bone age at 6โ€“12 monthly intervals
PBS status โœ” PBS General Benefit

Precocious Puberty

Precocious puberty is defined as the appearance of secondary sexual characteristics before age 8 years in girls or 9 years in boys. It requires timely evaluation to identify and treat potentially serious underlying causes and to mitigate psychosocial consequences and compromised adult height.

Type Mechanism Common Causes Key Features
Central (GnRH-dependent) Premature activation of the HPG axis; follows normal pubertal sequence Idiopathic (most common in girls); CNS tumours (hamartoma, astrocytoma); CNS infection; hydrocephalus; post-irradiation Progressive; symmetric development; advanced bone age; elevated LH response to GnRH stimulation test
Peripheral (GnRH-independent) Sex steroid production independent of HPG axis activation Congenital adrenal hyperplasia; McCune-Albright syndrome; adrenal tumours; gonadal tumours; exogenous sex steroids; familial male-limited precocious puberty May have atypical features (virilisation in girls, asymmetric development); suppressed gonadotrophins; autonomous sex steroid production
๐Ÿšจ
Red flags requiring urgent endocrine referral: Onset of puberty before age 6 in girls or 8 in boys; rapidly progressive development (Tanner staging advancing over <6 months); neurological symptoms (headache, visual disturbance, seizures); asymmetric breast development with cafรฉ-au-lait spots (McCune-Albright); virilisation in a girl.

Investigations for Precocious Puberty

Essential Bone age (left wrist X-ray) Advanced bone age (>2 SD above chronological age) supports diagnosis. MBS Item 57522.
Essential Basal LH, FSH, oestradiol (girls) / testosterone (boys) Elevated or pubertal-range basal LH suggests central precocious puberty.
Specialist GnRH stimulation test (gonadorelin test) Gold standard for confirming central precocious puberty; LH peak >5 IU/L is suggestive. Performed in paediatric endocrine unit.
Specialist MRI brain with pituitary protocol Mandatory in all boys with central precocious puberty and all children with onset <6 years to exclude CNS pathology.
Available 17-OHP, DHEAS, androstenedione To screen for congenital adrenal hyperplasia in peripheral precocious puberty with virilisation.
Available Pelvic / testicular ultrasound Assess for ovarian cysts (McCune-Albright), adrenal masses, or testicular tumours.

Treatment of Central Precocious Puberty

๐Ÿ’Š
Leuprorelin (GnRH agonist)
Lucrin Depot PDSยฎ ยท GnRH agonist
Mechanism Desensitisation of pituitary GnRH receptors suppresses gonadotrophin release and halts pubertal progression
Paediatric dose Leuprorelin acetate 11.25 mg IM every 3 months (depot formulation); or 3.75 mg IM every 4 weeks. Commence at paediatric endocrine direction.
Duration Continue until the appropriate age for puberty (typically 11โ€“12 years), then discontinue to allow pubertal reactivation
Monitoring Height, weight, Tanner staging, bone age (annual); LH and oestradiol/testosterone every 6 months; injection site reactions
PBS status โš  PBS Authority Required

Mental Health in Adolescents (Depression & Suicidality)

Mental health conditions are the leading cause of disability in Australian adolescents. The 2020โ€“2022 National Study of Mental Health and Wellbeing reported that approximately 39% of Australians aged 16โ€“24 had experienced a mental health disorder in the prior 12 months, with anxiety disorders most common, followed by affective disorders including major depressive disorder. The GP is the most frequently accessed health professional for mental health concerns in this age group.

Screening

Universal screening for depression and anxiety is recommended at least annually for all adolescents, and at every consultation for those with identified risk factors. Validated screening tools suitable for Australian general practice include:

Tool Age Items Cut-off Notes
PHQ-A (Patient Health Questionnaire โ€” Adolescent) 12โ€“18 9 items โ‰ฅ11 suggests major depression Most widely validated; freely available; also screens for anhedonia
KADS (Kutcher Adolescent Depression Scale) 12โ€“17 6 or 11 items โ‰ฅ6 (6-item version) Self-report; sensitive to change; good for monitoring
RCADS (Revised Children's Anxiety and Depression Scale) 8โ€“18 47 items (short form 25) T-scores โ‰ฅ70 = very elevated Screens both depression and anxiety subscales; useful for comorbid presentations
DASS-21 โ‰ฅ17 21 items Depression subscale: โ‰ฅ10 moderate Better suited to older adolescents and young adults

Depression โ€” Severity and Management

Mild
Mild Depression
PHQ-A 5โ€“9. Few symptoms; minor functional impairment; school attendance maintained. Often responds to watchful waiting, psychoeducation, sleep hygiene, and exercise.
Setting: GP review in 2โ€“4 weeks; self-help resources (ReachOut, MindSpot); lifestyle interventions
Moderate
Moderate Depression
PHQ-A 10โ€“19. Multiple symptoms; functional impairment (school, social withdrawal, sleep disturbance); persistent โ‰ฅ2 weeks. Requires psychological therapy; consider pharmacotherapy.
Setting: Mental Health Treatment Plan; refer for CBT or IPT-A; consider SSRI if insufficient response in 4โ€“6 weeks
Severe
Severe Depression / Acute Suicidality
PHQ-A โ‰ฅ20. Marked functional impairment; hopelessness; suicidal ideation with intent or plan; psychotic features; refusal to attend school. Requires combined pharmacotherapy and psychotherapy.
Setting: CAMHS / Headspace referral; consider paediatric admission if imminent risk; combine SSRI + CBT

Pharmacotherapy for Adolescent Depression

๐Ÿ’Š
Fluoxetine First-line
Prozacยฎ ยท Lovanยฎ ยท Zactinยฎ ยท SSRI
Indication Moderate-to-severe major depressive disorder in adolescents aged โ‰ฅ12 years, in combination with psychological therapy
Starting dose 10 mg PO once daily (morning) for 1 week, then increase to 20 mg once daily
Max dose 60 mg PO once daily (doses >20 mg should be prescribed under specialist guidance)
Duration Minimum 6โ€“12 months after symptom remission; taper over 4โ€“6 weeks when ceasing
Key interactions MAOIs (absolute contraindication); tramadol, triptans (serotonin syndrome risk); CYP2D6 inhibitors
Renal adjustment Use with caution in severe renal impairment; start at lower dose
PBS status โœ” PBS General Benefit
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Sertraline
Zoloftยฎ ยท Generic ยท SSRI
Indication Second-line SSRI for adolescent depression when fluoxetine is not tolerated or ineffective; specialist initiation recommended for patients <18 years
Starting dose 25โ€“50 mg PO once daily; titrate every 2โ€“4 weeks
Max dose 200 mg PO once daily
PBS status โœ” PBS General Benefit
๐Ÿšจ
Black box warning: All SSRIs carry a regulatory warning regarding increased risk of suicidal ideation and self-harm in children and adolescents during the initial weeks of treatment. Monitor weekly for the first 4 weeks, then fortnightly for the next 4 weeks, and regularly thereafter. Prescribe limited quantities (1โ€“2 weeks' supply initially). Involve family/carer in monitoring plan. Discuss the TGA Medicines Safety Alert with patients and families.

Suicide Risk Assessment

Any adolescent disclosing suicidal ideation, self-harm, or presenting with behavioural change suggesting depression must receive an immediate suicide risk assessment. The Columbia Suicide Severity Rating Scale (C-SSRS) is the recommended validated tool for Australian general practice and is freely available in a brief screener format.

1
Ask directly
"Have you been having thoughts that you would be better off dead, or of hurting yourself?" Direct questioning does not increase risk and is essential for disclosure. Use the C-SSRS screener (6 yes/no items).
2
Assess severity
Distinguish passive ideation ("wish I were dead") from active ideation with plan, intent, and access to means. Assess for protective factors (reasons for living, connectedness, future orientation).
3
Safety plan
Develop a collaborative safety plan (Stanley & Brown model): warning signs โ†’ internal coping strategies โ†’ social contacts for distraction โ†’ contacts for help โ†’ professional crisis contacts โ†’ means restriction. Provide in writing.
4
Involve supports
With the adolescent's consent, involve a parent, carer, or trusted adult. Document consent discussions. If there is imminent risk, breach confidentiality to protect life โ€” this is ethically and legally supported in all Australian jurisdictions.
5
Refer or escalate
Imminent risk: emergency department or crisis team. High risk without immediacy: CAMHS, Headspace, or private psychiatrist. Moderate risk: Mental Health Treatment Plan, close GP follow-up (within 1 week). Always arrange next contact before the patient leaves.
โš ๏ธ
Mandatory reporting: In all Australian states and territories, clinicians are required (or permitted) to breach confidentiality when there is a serious risk of harm to the patient or others. The threshold for breach is lower in paediatric/adolescent populations. Document your rationale for any breach and discuss it with the patient.

Psychological Therapies

  • Cognitive Behavioural Therapy (CBT): Most extensively studied and recommended first-line psychological treatment for adolescent depression. Typically 12โ€“16 sessions. Accessible via Mental Health Treatment Plans (up to 20 sessions per calendar year under Medicare, with possible additional sessions in exceptional circumstances).
  • Interpersonal Therapy for Adolescents (IPT-A): Effective alternative to CBT, particularly when interpersonal conflict or grief is prominent. Focuses on role transitions, interpersonal disputes, and grief.
  • Dialectical Behaviour Therapy (DBT-A): Evidence-based for recurrent self-harm and emotional dysregulation. Typically delivered as a structured programme in CAMHS or specialist settings.
  • Family-based interventions: Including Functional Family Therapy and Multisystemic Therapy for adolescents with conduct problems and depression comorbid with behavioural issues.

Key Australian Support Services

Service Details Access
Headspace National Youth Mental Health Foundation; free/low-cost services for 12โ€“25 year olds; mental health, physical health, alcohol and drugs, work/study support 150+ centres nationally; eheadspace online/phone
Kids Helpline Free, confidential counselling for 5โ€“25 year olds 1800 55 1800 (24/7); webchat; email
Lifeline Crisis support and suicide prevention 13 11 14 (24/7); text service 0477 13 11 14
Beyond Blue Depression, anxiety, and related disorders information and support 1300 22 4636; webchat; online forums
ReachOut Online mental health resources and peer support for young people au.reachout.com
CAMHS Child and Adolescent Mental Health Services (state-based public services) GP referral; varies by state/territory

Confidentiality & Risk Behaviours

The "Mature Minor" Doctrine in Australian Law

In Australia, there is no fixed age at which a young person can consent to medical treatment. Under common law (based on the UK Fraser guidelines, applicable across all Australian states and territories), a young person who demonstrates sufficient maturity and understanding โ€” a "mature minor" or "Gillick-competent" individual โ€” may consent to their own medical treatment without parental knowledge or approval. This applies to contraception, STI treatment, mental health care, and other interventions.

Key principles for assessing mature minor competence:

  • The adolescent must understand the nature, purpose, risks, and benefits of the proposed treatment.
  • The adolescent must understand the consequences of refusing treatment.
  • The assessment of competence is specific to the treatment proposed and the individual's maturity, not a blanket determination.
  • Younger adolescents (12โ€“14 years) may be competent for some decisions but not others; each consultation requires individual assessment.
  • Legislation varies by state/territory regarding specific age thresholds for particular interventions (e.g., sexual health, mental health treatment orders).
โ„น๏ธ
HANE framework: Structure the confidential adolescent consultation using History (open-ended questions, HEADSS), Assessment (clinical examination, screening tools), Neds (what does the young person need โ€” treatment, information, referral), and Engagement (maintain therapeutic alliance, arrange follow-up, involve supports with consent).

HEADSS Assessment

The HEADSS psychosocial interview is the recommended framework for systematic risk behaviour screening in adolescents. It should be introduced with an explanation of confidentiality and its limits, and conducted with the young person alone.

Domain Key Questions Red Flags
H โ€” Home Who do you live with? How are things at home? Do you feel safe? Family conflict; DV exposure; homelessness; out-of-home care
E โ€” Education/Employment Are you at school/working? How are you going? Any concerns? School refusal; declining performance; disengagement; bullying
A โ€” Activities What do you do for fun? Who are your friends? How much screen time? Social withdrawal; loss of interest; excessive gaming; isolation
D โ€” Drugs & Alcohol Have you ever used alcohol, tobacco, cannabis, or other substances? Regular use; binge drinking; vaping; illicit substance use; injecting drug use
S โ€” Sexuality Are you in a relationship? Are you sexually active? Do you use contraception? Unprotected sex; multiple partners; STI symptoms; sexual assault; gender dysphoria
S โ€” Suicide/Depression/Mood How is your mood? Have you felt hopeless? Have you had thoughts of self-harm or suicide? Self-harm; suicidal ideation; hopelessness; anhedonia; sleep disturbance; appetite change

Substance Use Screening โ€” CRAFFT 2.1

The CRAFFT 2.1 (Car, Relax, Alone, Forget, Friends, Trouble) is a validated 6-item screening tool for substance use in adolescents aged 12โ€“18 years recommended by the RACGP. A score of โ‰ฅ2 indicates a positive screen requiring further assessment.

  • C โ€” Have you ever ridden in a car driven by someone (including yourself) who was high or had been using alcohol or drugs?
  • R โ€” Do you ever use alcohol or drugs to relax, feel better about yourself, or fit in?
  • A โ€” Do you ever use alcohol or drugs while you are alone?
  • F โ€” Do you ever forget things you did while using alcohol or drugs?
  • F โ€” Do your family or friends ever tell you that you should cut down on your drinking or drug use?
  • T โ€” Have you ever gotten into trouble while you were using alcohol or drugs?
โš ๏ธ
Vaping update: E-cigarette use (vaping) among Australian adolescents has risen sharply, with recent surveys suggesting that up to 14% of 14โ€“17 year olds have vaped in the past month. The Australian Government has implemented reforms (2024) restricting sale of nicotine vaping products to pharmacies with a prescription. Ask specifically about vaping as part of substance use screening.

Key Risk Behaviours in Australian Adolescents

Sexual Health
  • Chlamydia is the most common notifiable STI in Australia; highest rates in 15โ€“24 year olds. Annual screening recommended for all sexually active adolescents.
  • HPV vaccination (Gardasil 9) on the NIP at age 12โ€“13 (school-based programme); catch-up available to age 25.
  • Contraception counselling should be offered proactively; LARCs (IUDs, implants) are first-line for adolescents per RANZCOG and WHO guidelines.
  • Cervical screening commences at age 25 in Australia (not 18), with HPV test replacing Pap smear.
Substance Use
  • Alcohol remains the most commonly used substance; binge drinking (>4 standard drinks on one occasion) is the most harmful pattern.
  • Cannabis is the most commonly used illicit substance; adolescent use is associated with increased risk of psychotic disorders and cognitive impairment.
  • Methamphetamine (ice) use, though less common, carries high risk of dependence and psychiatric complications; specific screening in high-risk populations.
  • Brief intervention (SBIRT model) is effective in primary care for adolescent substance misuse.

Preventive Health in Adolescents

Essential HPV vaccination (Gardasil 9) NIP-funded school programme at age 12โ€“13; 2-dose schedule (0 and 6โ€“12 months). Catch-up to age 25 if not previously vaccinated. MBS item N/A (school-based or GP administered, NIP-funded).
Essential Chlamydia screening (NAAT) Annual for sexually active adolescents <30 years; first-void urine or self-collected swab. Bulk-billed under MBS Item 69311.
Available Mental Health Treatment Plan (MHTP) MBS Item 2715 (GP Mental Health Treatment Plan); enables up to 20 sessions per calendar year of psychological therapy under Medicare.
Available Blood pressure, BMI, and growth monitoring Routine at every adolescent consultation; plot on age-appropriate growth charts. Hypertension screening from age 3 (USPSTF) but particularly important in obese adolescents.

Monitoring

Ongoing monitoring is essential for all adolescents under active management. The following schedule is recommended:

Week 1โ€“2
SSRI initiation: Review for side effects, suicidality, and tolerability. Brief telephone review acceptable. Ensure safety plan is current and family is informed (with consent).
Week 4
Early response assessment: Repeat PHQ-A or KADS. Assess sleep, appetite, concentration. If no improvement, consider dose optimisation or medication switch. Reassess suicidal ideation.
Week 8โ€“12
Therapeutic response: Expect meaningful improvement by week 8โ€“12. If inadequate, consider referral to CAMHS or paediatrician/psychiatrist. Review concurrent CBT engagement.
Month 3โ€“6
Continuation phase: Monthly reviews during continuation therapy. Monitor growth, weight, and developmental progress. Reassess risk behaviours and social functioning.
Month 6โ€“12
Maintenance/remission: If in remission, continue medication for a minimum of 6โ€“12 months. Plan tapering under specialist guidance. Reinforce relapse prevention strategies.
Annually
Routine adolescent health check: HEADSS assessment, substance screening (CRAFFT), sexual health review, vaccination status, growth and BP, mental health screening (PHQ-A), and education/career discussion.

Monitoring โ€” Delayed Puberty (on treatment)

  • Height, weight, and Tanner staging every 3โ€“6 months.
  • Bone age annually.
  • Hormone levels (testosterone, oestradiol, LH, FSH) every 6 months to guide dose titration.
  • FBC and LFTs at baseline and annually (particularly if on testosterone โ€” polycythaemia risk).
  • Psychosocial assessment of self-esteem, peer relationships, and school performance at each visit.

Monitoring โ€” Precocious Puberty (on GnRH agonist)

  • Tanner staging, height, and weight every 3 months.
  • Bone age every 6โ€“12 months.
  • GnRH agonist suppression (LH, oestradiol/testosterone) every 6 months to confirm adequate suppression.
  • Monitor injection site reactions; switch formulation if persistent granulomas.

Special Populations

๐Ÿ‘ถ

Early Adolescents (10โ€“13 years)

Puberty may just be commencing; developmental assessment should account for stage rather than chronological age.
Mental health presentations may manifest as irritability, somatic complaints, and school refusal rather than classic depressive symptoms.
Family involvement in management plans is usually more appropriate; balance with emerging autonomy.
SSRIs: fluoxetine is the only SSRI with strong evidence in this age group; specialist co-prescribing recommended.
๐Ÿณ๏ธโ€๐ŸŒˆ

LGBTQI+ Adolescents

LGBTQI+ young people experience significantly higher rates of depression, anxiety, self-harm, and suicidality (2โ€“4ร— the general population), driven largely by minority stress, discrimination, and rejection.
Use inclusive language; ask about chosen name and pronouns. Display visible signals of inclusivity in practice (e.g., rainbow tick, posters).
Gender-affirming care for transgender adolescents requires multidisciplinary team input (endocrinology, psychology, paediatrics). Puberty suppression (GnRH agonists) may be appropriate under specialist guidance.
Referral to specialist gender services (e.g., Royal Children's Hospital Melbourne Gender Service, Westmead Children's Hospital) and community supports (Minus18, QLife 1800 184 527).
๐Ÿฅ

Adolescents in Out-of-Home Care

Young people in out-of-home care (OOHC) have among the highest rates of mental health conditions, developmental delay, and chronic illness of any group in Australia.
Obtain a thorough history from case workers; previous trauma, abuse, and disrupted attachments are common.
Consent for treatment may involve the state/territory child protection agency as guardian; document consent pathways carefully.
Developmental assessments, dental health, and immunisation catch-up are priorities. Use the Australian Childhood Foundation guidelines for health assessments in OOHC.
๐ŸŒ

Refugee & CALD Adolescents

Adolescents from refugee and culturally and linguistically diverse (CALD) backgrounds may face unique stressors: pre-migration trauma, family separation, disrupted education, language barriers, and acculturation stress.
Use professional interpreters (not family members) for all sensitive consultations. TIS National (131 450) provides free interpreter services for Medicare-eligible consultations.
Mental health presentations may present with somatic complaints; validate symptoms while gently exploring psychological contributors.
Immunisation catch-up through the NIP is available free of charge; refer to the Australian Immunisation Handbook catch-up schedule.
๐ŸŒพ

Rural & Remote Adolescents

Adolescents in rural and remote Australia face geographic barriers to specialist services, including paediatric endocrinology and CAMHS.
Telehealth (Medicare-funded video consultations โ€” MBS Items 91790, 91800, 91801) can bridge access gaps for mental health and endocrine follow-up.
Headspace eheadspace provides free online and phone mental health support nationally.
GP-led shared care models with visiting specialists and Royal Flying Doctor Service may be necessary for complex endocrine or psychiatric management.
Aboriginal and Torres Strait Islander Health

Aboriginal and Torres Strait Islander adolescents experience significant health disparities compared with non-Indigenous Australians. The leading causes of death in Indigenous young people aged 15โ€“24 are suicide, transport accidents, and assault. Rates of self-harm, psychological distress, substance use, and teenage pregnancy are all significantly higher. These disparities are driven by the intergenerational impacts of colonisation, forced removal of children, systemic racism, socioeconomic disadvantage, and barriers to health care access.

โš ๏ธ
Cultural safety: Cultural safety is a core requirement of all interactions with Aboriginal and Torres Strait Islander adolescents. This includes acknowledging the social and emotional wellbeing (SEWB) framework, which recognises the connection between mental health and culture, community, Country, spirituality, and ancestors. Avoid framing all health concerns solely through a Western biomedical lens.
Self-harm and suicide
Aboriginal and Torres Strait Islander young people aged 15โ€“24 are approximately 4 times more likely to die by suicide than their non-Indigenous peers. Community-level, culturally grounded suicide prevention programmes (e.g., through Aboriginal Community Controlled Health Organisations โ€” ACCHOs) are more effective than individual clinical interventions alone.
Access to mental health services
Stigma, lack of culturally safe services, geographic remoteness, and historical mistrust of health systems are major barriers. ACCHOs provide holistic primary health care incorporating social and emotional wellbeing. Referral to Aboriginal Health Workers/Practitioners is encouraged. The Yarn Safe campaign (headspace) provides culturally appropriate mental health information.
Substance use
Indigenous adolescents report higher rates of alcohol, cannabis, and petrol/sniffing (in some remote communities). Brief intervention should be culturally adapted. The National Aboriginal and Torres Strait Islander Drug Strategy (2024) provides a framework for community-led harm reduction.
Sexual and reproductive health
Indigenous adolescents have higher rates of chlamydia, gonorrhoea, and teenage pregnancy. Contraception access, health literacy, and culturally safe sexual health education are essential priorities. The Australian STI Management Guidelines for Use in Primary Care (ASHM) include specific recommendations for remote Indigenous communities.
Developmental and chronic disease
Higher rates of rheumatic heart disease, chronic suppurative otitis media, trachoma, and renal disease may affect pubertal timing and psychosocial development. Growth monitoring using Indigenous-specific growth charts is recommended. Otitis media may contribute to language and learning difficulties affecting school engagement.
Strengths-based approaches
Focus on protective factors: connection to culture, community, language, and Country; strong kinship networks; engagement in cultural activities and sport; culturally affirming identity. These are powerful moderators of mental health risk and should be actively supported in clinical care.

๐Ÿ“š References

  1. 1. Sawyer SM, Afifi RA, Bearinger LH, et al. Adolescence: a foundation for future health. Lancet. 2012;379(9826):1630โ€“1640.
  2. 2. Australian Institute of Health and Welfare. Australia's youth: health, wellbeing and development. AIHW, Canberra; 2023.
  3. 3. Royal Australian College of General Practitioners. Guidelines for preventive activities in general practice. 9th ed. Melbourne: RACGP; 2016.
  4. 4. Palmert MR, Dunkel L. Clinical practice: delayed puberty. N Engl J Med. 2012;366(5):443โ€“453.
  5. 5. Carel JC, Eugster EA, Rogol A, et al. Consensus statement on the use of gonadotropin-releasing hormone analogs in children. Pediatrics. 2009;123(4):e752โ€“e762.
  6. 6. Cheung AH, Zuckerbrot RA, Jensen PS, et al. Guidelines for adolescent depression in primary care (GLAD-PC): II. Treatment and ongoing management. Pediatrics. 2018;141(3):e20174082.
  7. 7. Royal Australian and New Zealand College of Psychiatrists. RANZCP clinical practice guidelines for mood disorders. Melbourne: RANZCP; 2020.
  8. 8. National Health and Medical Research Council. National statement on ethical conduct in human research. Updated ed. Canberra: NHMRC; 2023.
  9. 9. Sanci L, Grabsch B, Chondros P, et al. The health care of young people in Australian general practice: results from the REACH study. Aust Fam Physician. 2009;38(1โ€“2):45โ€“48.
  10. 10. Stanley B, Brown GK. Safety planning intervention: a brief intervention to mitigate suicide risk. Cogn Behav Pract. 2012;19(2):256โ€“264.
  11. 11. World Health Organization. Health for the world's adolescents: a second chance in the second decade. Geneva: WHO; 2014.
  12. 12. Australian Institute of Health and Welfare. Aboriginal and Torres Strait Islander health performance framework. AIHW, Canberra; 2023.
  13. 13. Golden NH, Katzman DK, Sawyer SM, et al. Update on the medical management of eating disorders in adolescents. J Adolesc Health. 2015;56(4):370โ€“375.
  14. 14. Australian Government Department of Health and Aged Care. National Immunisation Program Schedule. Canberra: Department of Health; 2024.
  15. 15. Knight JR, Sherritt L, Shrier LA, et al. Validity of the CRAFFT substance abuse screening test among adolescent clinic patients. Arch Pediatr Adolesc Med. 2002;156(6):607โ€“614.
for PBS scripts. Utilise ACCHS pharmacies and Remote Area Aboriginal Health Worker programs for medication supply in remote areas. Avoid initiating benzodiazepines; support holistic pain management including community-based exercise programs.
Preventive health
Promote bone health: encourage vitamin D supplementation (1000 IU daily in deficient individuals), smoking cessation support, reduction of alcohol intake, and weight-bearing exercise. MBS Item 715 health checks provide a structured opportunity to assess bone health, screen for osteoporosis risk factors, and discuss musculoskeletal health in a culturally safe context.

Quick Reference: Differential Diagnosis at a Glance

Costovertebral dysfunction
Paracetamol ยฑ NSAID; manual therapy
2โ€“6 weeks
Provocable on palpation; no red flags
Thoracic compression fracture
Paracetamol; ยฑ calcitonin; DXA + osteoporosis Rx
6โ€“12 weeks healing
Elderly; osteoporosis; acute onset
ACS (posterior MI)
Aspirin 300 mg, GTN, heparin; urgent PCI
Time-critical
ECG, troponin; CV risk factors
Aortic dissection
IV labetalol; urgent CT aortogram; surgery (Type A)
Time-critical
Tearing pain; BP differential >20 mmHg
Vertebral osteomyelitis
IV antibiotics (vancomycin + ceftriaxone initially); ID consult
6 weeks IV antibiotics
Fever, elevated CRP, IV drug use
Biliary colic / cholecystitis
Paracetamol ยฑ morphine; lap cholecystectomy
Surgical within 72 h (cholecystitis)
RUQ/infrascapular; post-prandial; RUQ US

๐Ÿ“š References

  1. 1. Briggs AM, Smith AJ, Straker LM, Bragge P. Thoracic spine pain in the general population: prevalence, incidence and associated factors in children, adolescents and adults. A systematic review. BMC Musculoskelet Disord. 2009;10:77.
  2. 2. National Health and Medical Research Council (NHMRC). Evidence-based management of acute musculoskeletal pain. Canberra: NHMRC; 2003 (updated 2020).
  3. 3. Australian Institute of Health and Welfare (AIHW). Aboriginal and Torres Strait Islander Health Performance Framework: Summary report 2023. Canberra: AIHW; 2023.
  4. 4. Deyo RA, Rainville J, Kent DL. What can the history and physical examination tell us about low back pain? JAMA. 1992;268(6):760โ€“765.
  5. 5. Stochkendahl MJ, Kjaer P, Hartvigsen J, et al. National Clinical Guidelines for non-surgical treatment of patients with recent onset low back pain or lumbar radiculopathy. Europ Spine J. 2018;27(1):60โ€“75.
  6. 6. Erwin WM, Jackson PC, Homonko DA. Innervation of the human costovertebral joint: implications for clinical back pain syndromes. J Manipulative Physiol Ther. 2000;23(6):395โ€“403.
  7. 7. Royal Australian College of General Practitioners (RACGP). Guidelines for preventive activities in general practice. 9th edn. Melbourne: RACGP; 2018 (updated 2023).
  8. 8. Hirsch JA, Singh V, Falco FJE, et al. Thoracic facet joint interventions. Pain Physician. 2016;19(4):E581โ€“E593.
  9. 9. Erwin WM, Jackson PC. The costovertebral joint: anatomy, biomechanics, and clinical significance in thoracic back pain syndromes. J Can Chiropr Assoc. 2003;47(2):112โ€“120.
  10. 10. Strayer RJ, Gunnerson JM, Brown LH, et al. Aortic dissection: clinical features, diagnosis, and management. Aust Crit Care. 2019;32(2):144โ€“153.
  11. 11. Ombregt L. A system of orthopaedic medicine. 3rd edn. Edinburgh: Churchill Livingstone Elsevier; 2013. Chapter 18: Thoracic spine.
  12. 12. Lin CC, Chen KH, Li DM, et al. Characteristics and outcomes of patients presenting with thoracic back pain to the emergency department. Emerg Med Australas. 2020;32(5):805โ€“811.
for PBS-listed medicines at participating pharmacies.
Cultural safety
Engagement with Aboriginal Community Controlled Health Organisations (ACCHOs) is essential. Cultural safety training for non-Indigenous clinicians, use of Aboriginal Health Workers and Liaison Officers, and incorporation of traditional healing practices alongside Western medicine improve treatment adherence and outcomes. Avoidance of eye contact, respect for gender-sensitive examination practices, and understanding of sorry business protocols are critical elements of culturally safe care.
Medication adherence
Complex DMARD regimens with frequent monitoring requirements present adherence challenges. Long-acting depot injections (e.g., methotrexate SC) may improve adherence compared to oral regimens. Community pharmacy partnerships through the Indigenous Pharmacy Programmes improve medication management.
Specific conditions
Rheumatic heart disease (RHD) requires secondary prophylaxis with benzathine penicillin G (BPG) 1.2 MU IM every 3โ€“4 weeks for a minimum of 10 years or until age 21 (whichever is longer). RHD registers (e.g., NT RHD Register) facilitate recall and follow-up. The Australian RHD Endgame Strategy targets elimination by 2031.
Referral pathways
Referral through ACCHOs and Aboriginal Hospital Liaison Officers (AHLOs) improves engagement. The Specialist Outreach Assistance Programme provides funded specialist visits to remote communities. NT, WA, and QLD have specific rheumatology outreach programmes targeting Indigenous communities.

๐Ÿ“š References

  1. 1. Australian Institute of Health and Welfare (AIHW). Autoimmune disease in Australia. Cat. no. PHE 312. Canberra: AIHW; 2023.
  2. 2. Fraenkel L, Bathon JM, England BR, et al. 2021 American College of Rheumatology guideline for the treatment of rheumatoid arthritis. Arthritis Care Res. 2021;73(7):924โ€“939.
  3. 3. Fanouriakis A, Kostopoulou M, Alber K, et al. 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus. Ann Rheum Dis. 2019;78(6):736โ€“745.
  4. 4. Chung SA, Langford CA, Maz M, et al. 2021 American College of Rheumatology/Vasculitis Foundation guideline for the management of antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Care Res. 2021;73(11):1583โ€“1599.
  5. 5. Smolen JS, Landewรฉ RBM, Bijlsma JWJ, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update. Ann Rheum Dis. 2023;82(1):3โ€“18.
  6. 6. Australian Technical Advisory Group on Immunisation (ATAGI). Australian Immunisation Handbook. Australian Government Department of Health; 2024. Available from: immunisationhandbook.health.gov.au.
  7. 7. Rheumatic Heart Disease Australia (RHDAustralia). The 2020 Australian guideline for prevention, diagnosis, and management of acute rheumatic fever and rheumatic heart disease. 3rd ed. Darwin: Menzies School of Health Research; 2020.
  8. 8. Pharmaceutical Benefits Scheme (PBS). PBS Schedule. Australian Government Department of Health. Available from: pbs.gov.au. Accessed 2024.
  9. 9. Agarwal S, Cunnington J, Nossent J. Autoimmune disease in Indigenous Australians: a systematic review. Int J Rheum Dis. 2021;24(12):1487โ€“1498.
  10. 10. Pisetsky DS. Antinuclear antibody testing โ€” misunderstood or misused? Clin Immunol. 2023;255:109717.
  11. 11. Bertsias GK, Tektonidou M, Amoura Z, et al. Joint European League Against Rheumatism and European Renal Associationโ€“European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis. Ann Rheum Dis. 2012;71(11):1771โ€“1782.
  12. 12. Ledingham J, Deighton C; British Society for Rheumatology Standards, Audit and Guidelines Working Group. Update on the British Society for Rheumatology guidelines for prescribing TNFฮฑ blockers in adults with rheumatoid arthritis. Rheumatology. 2005;44(2):155โ€“158.
  13. 13. National Health and Medical Research Council (NHMRC). National statement on ethical conduct in human research. Canberra: NHMRC; 2023 (updated).
for PBS-listed medicines at participating pharmacies.
Cultural safety
Engagement with Aboriginal Community Controlled Health Organisations (ACCHOs) is essential. Cultural safety training for non-Indigenous clinicians, use of Aboriginal Health Workers and Liaison Officers, and incorporation of traditional healing practices alongside Western medicine improve treatment adherence and outcomes. Avoidance of eye contact, respect for gender-sensitive examination practices, and understanding of sorry business protocols are critical elements of culturally safe care.
Medication adherence
Complex DMARD regimens with frequent monitoring requirements present adherence challenges. Long-acting depot injections (e.g., methotrexate SC) may improve adherence compared to oral regimens. Community pharmacy partnerships through the Indigenous Pharmacy Programmes improve medication management.
Specific conditions
Rheumatic heart disease (RHD) requires secondary prophylaxis with benzathine penicillin G (BPG) 1.2 MU IM every 3โ€“4 weeks for a minimum of 10 years or until age 21 (whichever is longer). RHD registers (e.g., NT RHD Register) facilitate recall and follow-up. The Australian RHD Endgame Strategy targets elimination by 2031.
Referral pathways
Referral through ACCHOs and Aboriginal Hospital Liaison Officers (AHLOs) improves engagement. The Specialist Outreach Assistance Programme provides funded specialist visits to remote communities. NT, WA, and QLD have specific rheumatology outreach programmes targeting Indigenous communities.

๐Ÿ“š References

  1. 1. Australian Institute of Health and Welfare (AIHW). Autoimmune disease in Australia. Cat. no. PHE 312. Canberra: AIHW; 2023.
  2. 2. Fraenkel L, Bathon JM, England BR, et al. 2021 American College of Rheumatology guideline for the treatment of rheumatoid arthritis. Arthritis Care Res. 2021;73(7):924โ€“939.
  3. 3. Fanouriakis A, Kostopoulou M, Alber K, et al. 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus. Ann Rheum Dis. 2019;78(6):736โ€“745.
  4. 4. Chung SA, Langford CA, Maz M, et al. 2021 American College of Rheumatology/Vasculitis Foundation guideline for the management of antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Care Res. 2021;73(11):1583โ€“1599.
  5. 5. Smolen JS, Landewรฉ RBM, Bijlsma JWJ, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update. Ann Rheum Dis. 2023;82(1):3โ€“18.
  6. 6. Australian Technical Advisory Group on Immunisation (ATAGI). Australian Immunisation Handbook. Australian Government Department of Health; 2024. Available from: immunisationhandbook.health.gov.au.
  7. 7. Rheumatic Heart Disease Australia (RHDAustralia). The 2020 Australian guideline for prevention, diagnosis, and management of acute rheumatic fever and rheumatic heart disease. 3rd ed. Darwin: Menzies School of Health Research; 2020.
  8. 8. Pharmaceutical Benefits Scheme (PBS). PBS Schedule. Australian Government Department of Health. Available from: pbs.gov.au. Accessed 2024.
  9. 9. Agarwal S, Cunnington J, Nossent J. Autoimmune disease in Indigenous Australians: a systematic review. Int J Rheum Dis. 2021;24(12):1487โ€“1498.
  10. 10. Pisetsky DS. Antinuclear antibody testing โ€” misunderstood or misused? Clin Immunol. 2023;255:109717.
  11. 11. Bertsias GK, Tektonidou M, Amoura Z, et al. Joint European League Against Rheumatism and European Renal Associationโ€“European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis. Ann Rheum Dis. 2012;71(11):1771โ€“1782.
  12. 12. Ledingham J, Deighton C; British Society for Rheumatology Standards, Audit and Guidelines Working Group. Update on the British Society for Rheumatology guidelines for prescribing TNFฮฑ blockers in adults with rheumatoid arthritis. Rheumatology. 2005;44(2):155โ€“158.
  13. 13. National Health and Medical Research Council (NHMRC). National statement on ethical conduct in human research. Canberra: NHMRC; 2023 (updated).