📋 Key Information Summary
- Long-acting reversible contraception (LARC) — IUDs and subdermal implants — are the most effective reversible methods, with failure rates <1% per year in typical use.
- The combined oral contraceptive pill (COCP) has a typical-use failure rate of approximately 7–9% per year; perfect use achieves <1%.
- The etonogestrel subdermal implant (Implanon NXT®) provides ≥3 years of contraception and is PBS-listed as an Authority Required item.
- Levonorgestrel-releasing intrauterine systems (Mirena® 52 mg, Kyleena® 19.5 mg) are effective for 5–8 years depending on product and indication.
- Depot medroxyprogesterone acetate 150 mg IM (Depo-Provera®) is given every 12 weeks; counsel regarding potential bone mineral density reduction.
- The COCP is contraindicated with combined hormonal contraceptive use in women aged ≥35 years who smoke ≥15 cigarettes/day, or with BMI ≥35 kg/m² with additional risk factors for VTE.
- Emergency contraception with levonorgestrel 1.5 mg (Postinor-1®) is most effective within 72 hours; ulipristal acetate 30 mg (ellaOne®) extends efficacy to 120 hours.
- A copper intrauterine device (IUD) inserted within 5 days of unprotected intercourse is the most effective form of emergency contraception (failure rate <1%).
- All contraceptive methods require a shared decision-making approach considering efficacy, side-effects, reversibility, patient preference, and medical eligibility.
- Use the UKMEC or Australian-adapted eligibility criteria when prescribing combined hormonal contraception, particularly regarding VTE risk, migraine with aura, and hypertension.
- Aboriginal and Torres Strait Islander women experience higher rates of teenage pregnancy and reduced access to LARC in remote settings; culturally safe counselling is essential.
- Document contraceptive counselling including discussion of LARC in all women of reproductive age presenting for routine care or antenatal booking.
Introduction & Australian Epidemiology
Contraception is a core component of general practice and reproductive health care in Australia. Effective family planning reduces unintended pregnancies, supports reproductive autonomy, and improves maternal and perinatal outcomes. Australian general practitioners (GPs) play a central role in contraceptive counselling, prescribing, insertion of long-acting reversible contraception (LARC), and follow-up.
According to the Australian Institute of Health and Welfare (AIHW), approximately 4.0 million Australian women aged 15–49 use some form of contraception. The most commonly used methods are the combined oral contraceptive pill (COCP) and condoms, though uptake of LARC methods — particularly the levonorgestrel intrauterine system (LNG-IUS) and the etonogestrel subdermal implant — has increased significantly over the past decade, supported by GP training initiatives and PBS subsidies.
The national rate of induced abortions is estimated at approximately 15–20 per 1,000 women aged 15–44 years, with a significant proportion associated with contraceptive failure or non-use. The Royal Australian College of General Practitioners (RACGP) and Family Planning Australia recommend that discussions about contraception should be proactive, patient-centred, and inclusive of all available methods, with particular emphasis on LARC as first-line for most women.
This guideline provides Australian GPs and primary care clinicians with an evidence-based approach to contraceptive prescribing, including effectiveness comparisons, combined hormonal contraception, progestogen-only and LARC methods, and emergency contraception.
Effectiveness of Contraceptive Methods
Contraceptive effectiveness is best understood through both perfect-use and typical-use failure rates. Typical use reflects real-world adherence and includes user error. LARC methods (implants, IUDs, injectables) have the highest effectiveness because they remove the need for user action after initiation.
| Method | Perfect-Use Failure Rate (%/yr) | Typical-Use Failure Rate (%/yr) | Duration of Action | Reversibility |
|---|---|---|---|---|
| Etonogestrel implant (Implanon NXT®) | 0.05% | 0.05% | 3 years | Rapid (within days) |
| Copper IUD (Multiload® / Copper T) | 0.6% | 0.8% | 5–10 years | Immediate on removal |
| Levonorgestrel IUS — Mirena® 52 mg | 0.2% | 0.2% | 5 years (contraception); 8 years (if aged ≥45 at insertion) | Immediate on removal |
| Levonorgestrel IUS — Kyleena® 19.5 mg | 0.3% | 0.3% | 5 years | Immediate on removal |
| Depot medroxyprogesterone IM (Depo-Provera®) | 0.2% | 6% | 12 weeks per injection | Delayed (up to 6–12 months) |
| Combined oral contraceptive pill | 0.3% | 7–9% | Daily (continuous use possible) | Rapid (1–3 months) |
| Progestogen-only pill (desogestrel) | 0.3% | 7% | Daily | Rapid |
| Vaginal ring (NuvaRing®) | 0.3% | 7% | 21 days in / 7 days out | Rapid |
| Transdermal patch (Evra®) | 0.3% | 7% | Weekly × 3 / 1 week off | Rapid |
| Male condom | 2% | 13% | Per act | N/A |
| Female condom | 5% | 21% | Per act | N/A |
| Fertility awareness methods | 1–5% | 12–24% | Ongoing | Immediate |
Contraceptive Efficacy Tiers
Combined Oral Contraceptive Pill — Formulations & Prescribing
The combined oral contraceptive pill (COCP) contains an oestrogen (usually ethinyloestradiol or, in newer formulations, oestradiol valerate or estetrol) combined with a progestogen. It is one of the most widely prescribed medications in Australian general practice. The COCP works primarily by suppressing ovulation through inhibition of the hypothalamic–pituitary–ovarian (HPO) axis, as well as by thickening cervical mucus and thinning the endometrium.
Common Australian COCP Formulations
| Brand | Oestrogen | Progestogen | EE Dose (µg) | PBS Status | Notes |
|---|---|---|---|---|---|
| Levlen® ED | EE 30 µg | Levonorgestrel 150 µg | 30 | ✔ PBS General Benefit | Common first-line; standard 21/7 or continuous |
| Monofeme® | EE 30 µg | Levonorgestrel 150 µg | 30 | ✔ PBS General Benefit | Generic alternative to Levlen ED |
| Microgynon® 30 ED | EE 30 µg | Levonorgestrel 150 µg | 30 | ✔ PBS General Benefit | Widely prescribed |
| Brenda-35 ED® / Diane-35 ED® | EE 35 µg | Cyproterone acetate 2 mg | 35 | ✔ PBS General Benefit | Second-line; for acne/hirsutism. Higher VTE risk |
| Yasmin® | EE 30 µg | Drospirenone 3 mg | 30 | ✔ PBS General Benefit | Anti-androgenic; PMDD benefit; monitor potassium with other potassium-sparing drugs |
| Yaz® | EE 20 µg | Drospirenone 3 mg | 20 | ⚑ PBS Authority Required | 24/4 regimen; PMDD indication |
| Zoely® | Oestradiol 1.5 mg | Nomegestrol acetate 2.5 mg | ~Equivalent to EE 30 µg | ✔ PBS General Benefit | 24/4 regimen; native oestrogen; may suit women intolerant of EE |
| Nextstellis® | Estetrol 14.2 mg | Drospirenone 3 mg | ~Equivalent to EE 20–30 µg | ⚑ PBS Authority Required | 24/4 regimen; novel plant-derived oestrogen; lower hepatic impact |
Prescribing Principles
- Standard regimen: 21 active pills followed by a 7-day hormone-free interval (HFI). Pills are taken at the same time daily.
- Extended/continuous use: Running packs together (skipping the HFI) is safe and effective for reducing menstrual symptoms, dysmenorrhoea, and endometriosis-related pain. Counsel that breakthrough bleeding is common in the first 3–6 months.
- Starting the COCP: May be started on day 1 of the menstrual cycle (immediate protection) or on the "quick start" method (any day of the cycle, provided pregnancy is reasonably excluded and condoms are used for 7 days). The Sunday start method is rarely used in Australia.
- Missed pills: If one active pill is missed (<48 hours late), take it as soon as remembered and continue normally. If ≥2 active pills are missed or the pill is >48 hours late, take the most recent missed pill, discard earlier missed pills, use condoms for 7 days, and consider emergency contraception if unprotected intercourse occurred in the pill-free interval or first week of the missed pills.
- Low-dose formulations (EE 20 µg): Consider for women with oestrogen-related side-effects (nausea, breast tenderness, headache). Equivalent contraceptive efficacy; may have slightly higher rates of breakthrough bleeding.
Medical Eligibility — Key Contraindications (UKMEC Category 4)
- Current or past VTE (deep vein thrombosis, pulmonary embolism)
- Migraine with aura (at any age — significantly increased stroke risk)
- Smoker aged ≥35 years (≥15 cigarettes/day) — MEC Category 3–4
- Current breast cancer
- SLE with positive antiphospholipid antibodies
- Uncontrolled hypertension (≥160/100 mmHg)
- History of ischaemic heart disease or stroke
- Known thrombogenic mutations (Factor V Leiden homozygous, protein C/S deficiency)
- Undiagnosed abnormal uterine bleeding
- Major surgery with prolonged immobilisation (until 4 weeks post-mobilisation)
Common Side-Effects & Management
| Side-Effect | Management Strategy |
|---|---|
| Nausea | Take pill at bedtime with food; switch to lower-dose EE; consider progestogen-only or non-oral method |
| Breast tenderness | Usually resolves within 3 cycles; consider lower oestrogen dose |
| Headache | Assess for migraine with aura (UKMEC 4); consider continuous use to eliminate HFI headaches |
| Breakthrough bleeding | Reassure (common in first 3 months); ensure adherence; consider switching progestogen type |
| Mood changes / depression | Assess severity; consider progestogen-only or non-hormonal method; switch formulation |
| Reduced libido | Consider switching to androgen-neutral preparation or non-hormonal method |
| Weight gain (perceived) | Evidence does not support significant weight gain from COCP; reassure; address lifestyle factors |
Drug Interactions of Note
Contraceptive Counselling Checklist
- Discuss all methods including LARC as first-line options
- Assess medical history, smoking status, migraine history, VTE risk, BMI
- Provide written information (Family Planning Australia fact sheets)
- Discuss STI prevention (condoms in addition to contraception for new/multiple partners)
- Document discussion and patient's chosen method
- Arrange follow-up at 3 months and annually
Progestogen-Only & Long-Acting Reversible Contraception (LARC)
LARC methods — including the subdermal implant, intrauterine systems (both hormonal and copper), and the progestogen-only injectable — are the most effective reversible contraceptive options available in Australia. The RACGP and Faculty of Sexual and Reproductive Healthcare (FSRH) recommend LARC as first-line contraception for most women, including nulliparous women and adolescents. LARC methods have very high continuation rates at 12 months compared with user-dependent methods.
1. Etonogestrel Subdermal Implant — Implanon NXT®
Managing Unscheduled Bleeding on Implanon NXT®
- Reassure that irregular bleeding is the most common side-effect and often improves after 6–12 months
- Short courses of hormonal manipulation may help: ethinyloestradiol 20–30 µg daily for 20 days, or COCP for 1–3 months
- Tranexamic acid 1 g PO TDS during heavy bleeding episodes
- Mefenamic acid 500 mg PO TDS may reduce bleeding
- If persistent and unacceptable, consider removal and switching to an alternative LARC (e.g. LNG-IUS)
2. Levonorgestrel Intrauterine Systems (LNG-IUS)
IUS Insertion Counselling Points
- Timing: Ideally during menstruation (open cervical os, excludes pregnancy) or at any time with negative pregnancy test and reliable contraception in preceding 7 days
- Nulliparous women: IUS insertion is safe and appropriate. Consider paracervical block or intracervical local anaesthetic. Jaydess® and Kyleena® have smaller insertion tubes
- Pain management: Consider ibuprofen 400 mg PO 1 hour pre-insertion; intracervical lignocaine 1% (2 mL) block for nulliparous patients; oral misoprostol is NOT routinely recommended
- Follow-up: Check threads at 4–6 weeks post-insertion (post-menstruation); annual review; ultrasound if threads not visible
- Expulsion rate: ~2–10% in the first year, higher in the first 3 months. Check threads after each period
3. Copper Intrauterine Device (Cu-IUD)
The copper IUD (Multiload Cu375®, Copper T 380A) is a non-hormonal option effective for 5–10 years (depending on device). It is the most effective form of emergency contraception when inserted within 5 days of unprotected intercourse. The copper IUD is particularly suitable for women who prefer non-hormonal contraception or have contraindications to hormonal methods.
- Failure rate: 0.6–0.8% per year
- Side-effects: Heavier, longer, more painful periods (most common reason for removal); rare risk of perforation (~1:1,000)
- PBS status: ✔ PBS General Benefit — MBS item 35620 for insertion
- Contraindications: Wilson's disease, copper allergy, current pelvic infection, unexplained uterine bleeding, distorted uterine cavity
4. Depot Medroxyprogesterone Acetate (DMPA)
5. Progestogen-Only Pill (POP) — Desogestrel
Quick Reference — LARC Comparison
Emergency Contraception
Emergency contraception (EC) is used after unprotected sexual intercourse or contraceptive failure to prevent pregnancy. Three methods are available in Australia: levonorgestrel oral EC, ulipristal acetate oral EC, and the copper IUD. The copper IUD is the most effective method and should be offered wherever possible, particularly for women presenting within 120 hours of unprotected intercourse.
Emergency Contraceptive Methods
Emergency Contraception Decision Algorithm
- Emergency contraception is NOT an abortifacient — it prevents fertilisation/ovulation, not implantation of an established pregnancy.
- Efficacy decreases with delay — administer as soon as possible regardless of method chosen.
- Repeat dosing of levonorgestrel EC is safe if further UPSI occurs in the same cycle, but counsel regarding efficacy limitations.
- Do NOT combine levonorgestrel EC and ulipristal acetate — ulipristal acetate may be less effective if taken after levonorgestrel.
- Always discuss ongoing contraception after EC and provide a supply or prescription if appropriate.
Special Populations
Pregnancy
Adolescents & Young People
Women Aged >40 Years
Renal Impairment
Hepatic Impairment
Immunocompromised / HIV
Aboriginal and Torres Strait Islander Health
Aboriginal and Torres Strait Islander women experience significantly higher rates of teenage pregnancy, higher total fertility rates, and greater burden of sexually transmitted infections compared with non-Indigenous Australians. The AIHW reports that the teenage birth rate among Aboriginal and Torres Strait Islander women is approximately 4–5 times higher than non-Indigenous rates. Access to the full range of contraceptive options — particularly LARC — is reduced in remote and very remote communities due to workforce shortages, limited specialist and GP availability, and cultural barriers.
Culturally safe contraceptive counselling requires recognition of the social determinants of health, avoidance of judgemental language, and understanding of historical and ongoing impacts of colonisation, including forced sterilisation and child removal policies that may affect trust in reproductive health services.
Key Considerations for Practice
📚 References
- 1. Faculty of Sexual and Reproductive Healthcare (FSRH). FSRH Clinical Guideline: Intrauterine Contraception. London: FSRH; 2023 (amended 2024).
- 2. Faculty of Sexual and Reproductive Healthcare (FSRH). FSRH Clinical Guideline: Combined Hormonal Contraception. London: FSRH; 2019 (amended 2023).
- 3. World Health Organization. Medical Eligibility Criteria for Contraceptive Use. 5th ed. Geneva: WHO; 2015.
- 4. Australian Institute of Health and Welfare (AIHW). Contraception and Reproductive Health in Australia. Cat. no. PER 106. Canberra: AIHW; 2023.
- 5. Peipert JF, Zhao Q, Allsworth JE, et al. Continuation and satisfaction of reversible contraception. Obstet Gynecol. 2011;117(5):1105-1113. doi:10.1097/AOG.0b013e31821188ad
- 6. Royal Australian College of General Practitioners (RACGP). Prescribing Drugs of Dependence in General Practice, Part C2: The Role of Drugs in Contraception. Melbourne: RACGP; 2020.
- 7. Trussell J. Contraceptive failure in the United States. Contraception. 2011;83(5):397-404. doi:10.1016/j.contraception.2011.01.021
- 8. Glasier A, Cameron ST, Blithe D, et al. Can we identify women at risk of pregnancy despite using emergency contraception? Data from randomized trials of ulipristal acetate and levonorgestrel. Contraception. 2011;84(4):363-367. doi:10.1016/j.contraception.2011.02.009
- 9. Family Planning Alliance Australia. National Contraceptive Guidelines for Australian General Practice. Sydney: FPAA; 2023.
- 10. Department of Health and Aged Care, Australian Government. Closing the Gap: National Agreement on Closing the Gap — Target 2: Increase in proportion of Aboriginal and Torres Strait Islander babies with a healthy birthweight. Canberra: Commonwealth of Australia; 2020.
- 11. Australian Commission on Safety and Quality in Health Care (ACSQHC). National Safety and Quality Health Service Standards. 2nd ed. Sydney: ACSQHC; 2021.
- 12. Cleland K, Zhu H, Goldstuck N, Cheng L, Trussell J. The efficacy of intrauterine devices for emergency contraception: a systematic review of 35 years of experience. Hum Reprod. 2012;27(7):1994-2000. doi:10.1093/humrep/des140
- 13. Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG). Contraception and the Perimenopause — C-Gyn 35. Melbourne: RANZCOG; 2022.
- 14. Pharmaceutical Benefits Scheme (PBS). Schedule of Pharmaceutical Benefits for Approved Pharmacists and Medical Practitioners. Australian Government Department of Health; effective 1 March 2025.
- 15. Australian STI Management Guidelines for Use in Primary Care. STI Screening in Priority Populations. Sydney: ASHM; updated 2024. Available at: https://www.sti.guidelines.org.au/